Esophagus Stomach Duodenum Capsule Endoscopy Inflammatory Bowel Disease Colon & Ileum Miscellaneous

Signet Ring Adenocarcinoma

63 year-old undergoing average risk colon screening.

Left: Approaching the cecum, mild mucosal elevation was noted from the forward view. The ileocecal valve is visible in the distance in the left side of the image.

Center: Retroflexing the instrument enabled visualization of this 1 cm sessile polypoid lesion in the proximal ascending colon.

Right: Close up view. Note the raised center of the lesion, and the raised edges. Biopsies from the edges revealed carcinoma undermining normal tissue. The histology was a poorly differentialed adenocarcinoma with prominent signet ring features. Immunohistochemical stains indicated the lesion to be of primary colonic origin.

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