Granular Cell Tumor of Esophagus
Left: 29 year-old woman with gastroesophageal reflux symptoms. Endoscopy revealed changes of Barrett's disease, and this 1 cm raised, firm, yellow lesion in the mid-esophagus. On biopsy, this proved to be a granular cell tumor.
Right: Smooth, sessile, yellow-white polypoid lesion in the proximal esophagus of a 39 year-old woman undergoing endoscopy for evaluation of acid-peptic symptoms.
Granular cell tumors are of neural origin from Schwann cells, usually behave in a benign fashion, and can arise virtually anywhere in the body, including skin, oral cavity, breast and GI tract. Although the esophagus may be the most common gastrointestinal site, granular cell tumors may occur elsewhere, including the colon.
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