77 year-old man with dysphagia (difficulty in swallowing), who had previously undergone radiation therapy for carcinoma of the lung. Endoscopy revealed esophageal inflammation, with vascular hyperplasia.
60 year-old woman with dysphagia, who had undergone radiation therapy for carcinoma of the lung several years earlier. Endoscopy revealed a segment of severe inflammation confined to the proximal third of the esophagus, with an abrupt transition from normal to inflamed mucosa (LEFT), severe inflammation with exudation (CENTER), and relative narrowing of the lumen (RIGHT).
Same patient as above, 16 months later. The stricture was recurrent and required repeat dilation, despite the marked reduction in the severity of mucosal inflammation.
48 year-old man with multiple myeloma, who had received radiation therapy for a plasmacytoma involving the 10th thoracic vertebra, developed severe dysphagia and odynophagia several months later. Endoscopy revealed severe esophagitis. Brushings were benign and negative for virus and fungal elements.
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