67 year-old woman with six months of increasing dysphagia, epigastric pain and weight loss. Endoscopy revealed a partially obstructing neoplasm in the midesophagus (left), a relatively normal distal esophagus, and a poorly distensible stomach with a proximal gastric mass (center and right). The gastric mass was difficult to view en face due to poor distensibility of the stomach. Biopsy of both lesions showed squamous cell carcinoma on biopsy.

74 year-old woman with abdominal pain and weight loss, and a prior history of carcinoma of the breast. Endoscopy revealed an infiltrating process involving the proximal gastric body. Shown here is the transition from carcinoma to normal mucosa. Biopsies were consistent with metastatic adenocarcinoma of the breast.

79 year-old woman with known extensive, metastatic colonic carcinoma, presenting with upper gastrointestinal bleeding.